Four medical oncologists- Dr. Jamil Asselah from MUHC, Quebec, Dr. Katarzyna Jerzak from Sunnybrook, Ontario, Dr. Arif Awan from Ottawa Hospital, and Dr. Pedro Moraes from São Paulo - discuss key abstracts from SABCS. Highlights include the HER2CLIMB-05 trial for HER2-positive metastatic breast cancer, the lidERA study of an oral SERD (giredestrant) in the adjuvant setting, and the ASCENT-07 trial of sacituzumab govitecan.