Breast cancers are molecularly diverse at multiple levels
Several Key challenges to translate genomic data
The challenges in ER+ve breast cancer care?
- Development of stratified therapeutics for patients to account for inter-tumoural heterogeneity, building on past successes to accelerate the delivery of the right drug to the right patient at the right time based on targeting key molecular drivers.
- Build frameworks to devise combination therapies to account for intra-tumoural heterogeneity, seeking to target multiple tumour vulnerabilities sequentially or at the same time, being cognizant of the potential for combinatorial toxicities as well as benefit.
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